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Yet the program hasnt been a total success. The first family that relocated to Dothan in early 2009 had to leave town because of job scarcities during the recession, said Goldsmith, and the economic downturn slowed interest in the program to a trickle for years.
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Scientists in Lawrence’s lab had previously identified that mechanism as the XIST gene, a piece of DNA located in the X chromosome that controls whether or not the chromosome can be silenced.  The XIST gene makes a unique non-coding RNA, which accumulates in the nucleus of the cell of the chromosome, triggering changes to the way the chromosome is packaged within the cell.  This ultimately renders the chromosome inactive – preventing its DNA from producing proteins and other components.
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