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zoloft 25 mg effective Hoping to recreate this effect, Lawrence and her colleague Lisa Hall, research assistant professor of cell and developmental biology at UMMS, devised a way to insert the XIST gene into the extra chromosome 21 of trisomic cells.  In a culture of pluripotent stem cells derived from the skin cells of a Down syndrome patient, the XIST gene was inserted into the chromosomes through the use of zinc finger nuclease (ZFN) technology. The technique ultimately allowed them to cut each chromosome at a specific location in its sequence and then paste the gene into that cut site.
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